Transfer rumours involving Anders Lindegaard and Manchester United broke in November 2010 as it was reported that the Danish goalkeeper was a target for the Red Devils. On November 23, 2010, various British media outlets reported that Manchester United were closing in on a move for the player and that the transfer could be completed in the next two to three weeks. Four days later, Manchester United secured his transfer for an undisclosed fee believed to be around £3.5m and he signed for three-and-a-half years until the end of the 2013/14 season. Anders Lindegaard was signed from Aalesund in the Norwegian league.
Lindegaard made his home debut in the colours of Manchester United during the FA Cup fifth round clash with National Conference side Crawley Town. The match which was played on February 19, 2011 ended in a 1-0 win for the Red Devils. In the following month, Anders Lindegaard underwent a knee surgery that ruled him out of action for five weeks. He returned to play in the Senior Cup final as the Manchester United reserves beat Bolton Wanderers reserves 3-1 to win the competition.
Anders Lindegaard earned a lot of plaudits after his impressive performance on the occasion of his Champions League debut for the Red Devils. He made a lot of saves as Manchester United and Portuguese team Benfica played out a 1-1 draw at the end of the game played on September 14, 2011.